Kosenko P.N., Vavrinchuk S.A. Age-related particularities of electrogastroenterography parameters // Journal of Gastroenterology and Hepatology 2013; Vol. 28 (Suppl. 3): p. 694.

Gastro 2013 APDW/WCOG Shanghai,
Asian Pacific Digestive Week 2013 | World Congress of Gastroenterology,
21-24 September 2013, Shanghai Expo Center, Shanghai, China

PR0001
Basic Neurogastroenterology (Nerve-Gut, Motility)

Age-related particularities of electrogastroenterography parameters

Presenting Author: Pavel Mihajlovich Kosenko 
Additional Authors: Sergey Andreevich Vavrinchuk 
Corresponding Author: Pavel Mihajlovich Kosenko
Affiliations: Far Eastern State Medical University; Postgraduate Institute for Public Health Workers

Objective: Study objective – to study the age related particularities of electrogastroenterography (EGEG) parameters and its effect on electrophysiological evaluation of gastrointestinal motor function.

Methods: The study involved 15 young (age 18–23 years) and 15 old (age 69–75 years) practically healthy people. The criteria of inclusion of the study were the absence of organic and functional gastrointestinal diseases in the anamnesis. To evaluate the gastrointestinal tract motor functions we used EGEG method with evaluation of parameters for basal and stimulated electric activity (EA) of gastrointestinal sections. Standard food load was used as the stimulator of GMF. We used the following parameters: Ps (mV) – total level of gastrointestinal EA; Pi (mV) – EA by gastrointestinal sections, Pi/Ps (%) – rate of each frequency spectrum in total spectrum; Krhythm – ratio of spectrum curve to the length of spectrum part for studied, Pi/P(i + 1) – ratio of EA of superior gastrointestinal section to inferior.

Results: When comparing the EGEG parameters in two groups using Mann – Whitney U-test we found no statistically significant differences between groups of old and young people. Using the discrimination analysis (DA) we detected 5 variables in which the groups of young and old studied people possessed statistically significant differences. The parameters involved basal parameters – Pi of colon, Pi/Ps of stomach, Pi/P(i + 1) jejunum/ileum, Krhythm of duodenum and colon, as well as stimulated parameters – Pi/Ps of duodenum and Pi/P(i + 1) duodenum/jejunum. Based on the DA we created the mathematical models of duodenal stenosis. Use of detected age-related particularities of EGEG parameters allowed us to increase the accuracy of proposed distribution of patients with stenosis from 85.2% to 92.8%.

Conclusion: Thus there are the age-relevant particularities of EGEG parameters that need to be taken in account during interpretation of the results of electrophysiological evaluation of GMF.

Key Word(s): 1. electrophysiology; 2. electrogastrography; 3. electroenterography;