Johnson LF, DeMeester TR. Development of 24-hour intraesophageal pH monitoring composite scoring system. Esophageal Disorders: Pathophysiology and Therapy / Ed. by TR DeMeester and DB Skinner, NY: Raven Press; 1985. P. 561-70.

Авторы: Johnson L.F. / DeMeester T.R.

Development of 24-hour Intraesophageal pH Monitoring Composite Scoring System

Lawrence F. Johnson and *Tom R. DeMeester


Gastroenterology Service, Department of Medicine, Walter Reed Army Medical Center.
Washington, D.C. 20307: the Uniformed Services University of the Health Sciences.
Bethesda, Maryland 20814; and *Departmem of Surgery, Creighton University, Omaha, Nebraska 68131

While 24-h intraesophageal pH monitoring provided the desired goal of objectively measuring the marker of gastroesophageal reflux (GER) disease, i.e., reflux of acid gastric contents into the distal esophagus, the technique presented a complex problem as to how to define or score that objectivity. The 24-h pH composite score, developed to address this issue¹, has been briefly described in both oral presentations and published reports, but program time limits and journal space restrictions have prevented a detailed description of the logic involved in its derivation. This chapter provides an opportunity to reexamine the logic and merits of the score, especially in light of recent advances in our understanding of the pathophysiology of GER disease.

Physiologic reflux in an asymptomatic subject. This portion of the pH record shows LES competence during sleep and four episodes of reflux after breakfast.²

См. далее в новом окне (формат pdf, 2,44 Mb): Johnson LF, DeMeester TR. Development of 24-hour intraesophageal pH monitoring composite scoring system (1985).


¹ Johnson LF, DeMeester TR. Twenty-four-hour pH Monitoring of the Distal Esophagus: A Quantitative Measure of Gastroesophageal Reflux. The American Journal of Gastroenterology. Volume 62, Issue 4, October 1974, P.325-332.
² График «Физиологические рефлюксы утром у бессимптомного пациента» получен на аппаратуре для 24-часовой рН-метрии, изображённой на фотографии: «24-часовая рН-метрия пищевода в Армейском медицинском центре имени Триплера (англ. Tripler Army Medical Center), в Гонолулу, Гавайи, США».

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См. также: Johnson LF, DeMeester TR. Development of the 24-hour intraesophageal pH monitoring composite scoring system. J Clin Gastroenterol 1986; 8(Suppl 1):52-58.

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